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twistedknob

Tin Man

Posts: 14 Member Since:17/08/2012

#122 [url]

Oct 3 13 1:47 AM

As shown at avclub.com :

Scientists may have found the cure for deafness caused by too many rock shows, loud noises

Here’s some news that should be exciting to all readers hearing a gentle high-pitched ringing right now: Scientists in Britain think they may have found a cure for deafness caused by loud noises, infections, and toxic drugs. In tests, a treatment codenamed LY411575 has been shown to reverse deafness in mice. Neuroscience journal Neuron says that the drug may very well work on humans, but that more research is still needed. Still, its mere existence should be music to the ears of anyone who’s having trouble hearing that music, after years of headphone use or basement shows.
Deafness occurs—in these cases, at least—when sensory hair cells within the ear have been lost. Previously, those cells didn’t redevelop, meaning once they were gone they were gone. But LY411575 has been seen to regenerate those cells in mice and restore hearing. The drug works by blocking a protein called Notch, which cruelly prevents stem cells from becoming new sensory hair cells within the cochlea.
Hearing loss affects 250 million people worldwide. Deafness Research UK says that about 87 percent of Britons have some level of deafness, due most likely to exposure to loud noises.

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Starman99

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Posts: 2 Member Since:12/03/2017

#126 [url]

Mar 12 17 6:56 PM

@ dr funk

Was googling 'Dr Wilden' and found this very interesting thread. Great to read that your hearing issues were sorted by laser therapy.

I'm a professional musician with some hearing issues (hyperacusis, mainly) and am thinking of going to Amon Kaiser's clinic in Germany for laser therapy (Amon Kaiser is Dr Wilden's son). I must confess I'm a little in two minds about going as the treatment is very expensive and there's not much in the way of evidence of its efficacy out there. So... I'm very interested to hear experiences of people who have been to see Dr Wilden or his son...

So just to silence the skeptic in me, I hope you don't mind if I play devil's advocate for a second and ask you: Can you be reasonably sure that the treatment you received from Dr Wilden was responsible for your improvement? Or could you have just been getting better anyway?

Also, I'm wondering if the good effects were maintained afterwards, or if you had to go back for further treatment. Many thanks! :)

Last Edited By: Starman99 Mar 14 17 10:35 AM. Edited 2 times.

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dr funk

Platinum Blonde

Posts: 1,624 Member Since:24/12/2011

#127 [url]

Mar 13 17 5:07 PM

Starman99 wrote:

So just to silence the skeptic in me, I hope you don't mind if play devil's advocate for a second and ask you: Can you be reasonably sure that the treatment you received from Dr Wilden was responsible for your improvement? Or could you have just been getting better anyway?



Funnily enough, that's something I've also thought about over the years. By the time I arrived in Germany, I had naively been blasting my ears for months to compensate for the hearing loss in my left ear. One of the first things Dr Wilden told me to do was to wear earplugs everywhere during treatment, to give my ear a chance to start recovering.

So yes, I would have to say that the possibility that I was "just getting better anyway" was a factor. However, I could feel that my ears were definitely reacting to the laser, especially during the second week of treatment. I could feel my eardrums pulsating and I could hear 'chirping' sounds, which Dr Wilden said was a great sign that my ears were responding to the laser.

Starman99 wrote:

Also, I'm wondering if the good effects were maintained afterwards, or if you had to go back for further treatment. Many thanks! :)
 

 


When I returned home, my hearing felt completely normal, as if nothing had ever happened. And the effects were indeed maintained afterwards.

Another thing I would add is that I was receiving monthly hospital audiograms, as my progress was still being monitored monthly by an ENT consultant. When I returned from Germany, I had a hospital appointment three days later, and the audiologist was astonished at the result of my audiogram. She said "you HAVE to talk to the consultant about this", so I did, and the consultant's reaction to my story of laser treatment was simply "oh, I see". He had no interest in finding out more about laser treatment, but at least he was happy for me...

Hope this helps!

Frank

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Starman99

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Posts: 2 Member Since:12/03/2017

#128 [url]

Mar 14 17 12:33 AM

Thanks for the reply. All very interesting. And it's great to read a success story!

I think I'll just have to try the laser therapy and see what happens!

Last Edited By: Starman99 Mar 14 17 10:37 AM. Edited 1 time.

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